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UNBS5162
产品别名
956590-23-1
UNBS5162
UNBS 5162
[2-[2-(Dimethylamino)ethyl]-1,3-dioxobenzo[de]isoquinolin-5-yl]urea
N-[2-[2-(Dimethylamino)ethyl]-2,3-dihydro-1,3-dioxo-1H-benz[de]isoquinolin-5-yl]urea
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C17H18N4O3 |
Molecular weight | 326.35 |
MDL number | MFCD22380608 |
Biochem/physiol Actions【生化/生理作用】 | UNBS5162, an amonafide (naphthalimide) derivative, is a potent antitumor agent that inhibits tumor proliferation, progression and invasiveness. UNBS5162 is a pan-antagonist of CXCL chemokine expression. It appears that UNBS5162 inhibits melanoma progression through inhibition of the AKT/mTOR signaling pathway. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | −20℃ |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |