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WYC-209
产品别名
2131803-90-0
WYC-209
2-[2-(3,4-Dihydro-4,4-dimethyl-1-oxido-2H-1-benzothiopyran-6-yl)ethynyl-5-pyrimidinecarboxylic acid, ethyl ester
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C20H20N2O3S |
Molecular weight | 368.45 |
Biochem/physiol Actions【生化/生理作用】 | WYC-209 is a synthetic retinoid with antiproliferative activity and better inhibition of cancer cell growth and proliferation than Tazarotene or ATRA (all-trans-retinoic acid). WYC-209 was shown to inhibit proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 value of 190 nM and also inhibited proliferation of TRCs of human melanoma, lung cancer, ovarian cancer, and breast cancer in culture. Synthetic retinoid with antiproliferative activity |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | O=S1CCC(C)(C)C2=C1C=CC(C#CC3=NC=C(C(OCC)=O)C=N3)=C2 |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |