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APX2009
产品别名
APX2009
2-[(1,4-Dihydro-3-methoxy-1,4-dioxo-2-naphthalenyl)methylene]-N,N-diethyl-pentanamide
(2E)-2-[(3-methoxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methylidene]-N,N-diethylpentanamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H25NO4 |
| Molecular weight | 355.43 |
| Biochem/physiol Actions【生化/生理作用】 | APX2009 is a cell penetrant potent and selective second-generation inhibitor of APE1 redox-signaling that stimulates APE1 DNA repair activity. APX2009 is neuroprotective against cisplatin and oxaliplatin induced toxicity. APX2009 exhibits potent antitumor activity in neuroblastoma cell lines and 3D spheroid pancreatic tumor model. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C1C(OC)=C(/C=C(CCC)/C(N(CC)CC)=O)C(C2=C1C=CC=C2)=O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
