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AQ1 trifluoroacetic acid salt
产品别名
1338367-84-2
AQ1 trifluoroacetic acid salt
2,2′-(9,10-dihydro-9,10-dioxo-1,5-anthracenediyl)bis[L-lysyl-β-alaninamide trifluoroacetic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C32H44N8O6 · xC2HF3O2 |
| Molecular weight | 636.74 (free base basis) |
| Biochem/physiol Actions【生化/生理作用】 | AQ1, an anthraquinone derivative, is a potent stabilizer of c-KIT G-quadruplexes (G4) that downregulates c-KIT mRNA and protein expression in human and canine cell lines. Also, AQ1 causes inhibition BCL2 gene expression in HGC27 and MCF7 cells. AQ1 inhibits proliferation of in varies human tumor cell lines including HCG27, MCF7 and imatinib resistant HMC1.2 cells. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | faint yellow to dark orange |
| solubility【溶解性】 | H2O: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
