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Aurothioglucose hydrate
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086583 | 5 MG | 1510 | |||
| 4086583 | 25 MG | 4910 |
产品别名
12192-57-3
Aurothioglucose hydrate
Solganol
Solganal
Gold thioglucose
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C6H11AuO5S · xH2O |
| Molecular weight | 392.18 (anhydrous basis) |
| EC number【EC 号】 | 235-365-7 |
| PubChem Substance ID【PubChem化学物质编号】 | 24724383 |
| NACRES | NA.77 |
| Application【应用】 | Aurothioglucose hydrate has been used in redox stress survival assay in human cell lines and for inducing obese phenotype in mice. |
| Biochem/physiol Actions【生化/生理作用】 | Aurothioglucose, a gold compound used clinically to treat rheumatoid arthritis, has recently been found to be a potent PKCiota-Par6 interaction inhibitor, with an IC50 approximately 1 μM. Disruption of this interaction disrupts a rac1 signaling pathway that is required for transformed growth in non-small-cell lung cancer. |
| Features and Benefits【特点和优势】 | This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥96% (titration) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 5 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O.OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O |
| InChI | 1S/C6H12O5S.Au.H2O/c7-1-2-3(8)4(9)5(10)6(12)11-2;;/h2-10,12H,1H2;;1H2/q;+1;/p-1/t2-,3-,4+,5-,6-;;/m1../s1 |
| InChI key | SGVIEHTYEMEDRR-PKXGBZFFSA-M |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H317 - H334 |
| Precautionary Statements | P261 - P280 - P342 + P311 |
| Hazard Classifications【危险分类】 | Resp. Sens. 1 - Skin Sens. 1 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
