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BMS-281384 bis-HCl
产品别名
261769-44-2
BMS-281384 bis-HCl
4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-1-ethyl-N-(4-pyridinylmethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide bis-HCl
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H23ClN6O2 · 2HCl |
| Molecular weight | 523.84 |
| PubChem Substance ID【PubChem化学物质编号】 | 329774357 |
| Biochem/physiol Actions【生化/生理作用】 | BMS-281384 is a selective and potent phosphodiesterase 5 (PDE 5) inhibitor. BMS-281384 was found to have an IC50 value of 0.8 nM for PDE5 and 47 to 9200-fold selective over other PDEs 1-6. |
| Features and Benefits【特点和优势】 | BMS-281384 is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS. |
| Legal Information【法律信息】 | Sold for research purposes only under agreement from BMS. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | room temp |
| SMILES string | [H]Cl.[H]Cl.ClC1=C(OC)C=CC(CNC2=C(C=NN3CC)C3=NC=C2C(NCC4=CC=NC=C4)=O)=C1 |
| packaging【包装】 | 5, 25 mg in glass bottle |
