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C18 Dihydroceramide (d18:0/18:0)
产品别名
2304-80-5
C18 Dihydroceramide (d18:0/18:0)
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C36H73NO3 |
| Molecular weight | 567.97 |
| General description【一般描述】 | C18 Dihydroceramide (d18:0/18:0) or N-Stearoylsphinganine is a synthetic lipid. Acylation of sphinganine with stearoyl (FA-CoA with C18 acyl chain) by dihydro ceramide synthase 1, yields C18-dihydroceramide. |
| Application【应用】 | C18 Dihydroceramide (d18:0/18:0) has been used as a standard for the quantitation of sphingolipid metabolites in adipose tissues by quadrupole time-of-flight (Q-TOF) mass spectrometry. |
| Biochem/physiol Actions【生化/生理作用】 | Dihydroceramides act as precursors for ceramides in the mammalian de-novo sphingolipid pathway. vitamin D supplementation increases plasma C18 dihydroceramide (C18-DHC) levels in type 2 diabetes mellitus (T2D) patients. Low serum concentration of C18-DHC has been observed in patients with history of graft rejection and ischemic type biliary lesions (ITBL). Therefore, it can be used as a predictor of graft rejection. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 860627P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860627P-25mg) 5 mL Amber Glass Screw Cap Vial (860627P-5mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
