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Eupatilin

产品编号:4086721
规格:≥98% (HPLC)
CAS NO:22368-21-4
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40867215 MG1210
408672125 MG5620
产品别名

22368-21-4

Eupatilin

2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one

NSC 122413

5,7-Dihydroxy-3′,4′,6-trimethoxyflavone

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C18H16O7
Molecular weight
344.32
MDL number
MFCD13194819
PubChem Substance ID【PubChem化学物质编号】
329826018
NACRES
NA.77
Application【应用】
Eupatilin has been used to investigate its inhibitory effects on intracranial hemorrhage (ICH)-induced inflammation and its anti-inflammatory mechanisms in mouse BV2 cells, in vitro. It has also been used as a standard for its quantitative estimation in Artemisia extracts by microcolumn high performance liquid chromatography with diode array (HPLC-DAD) assay.
Biochem/physiol Actions【生化/生理作用】
Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis.
Eupatilin is a flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
(Isolated from Artemisia sp.)
Assay【测定】
≥98% (HPLC)
form【形式】
powder
storage condition【储存条件】
desiccated
protect from light
color【颜色】
white to beige
solubility【溶解性】
DMSO: 20 mg/mL, clear
storage temp.【储存温度】
−20℃
SMILES string
O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C31
InChI
1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3
InChI key
DRRWBCNQOKKKOL-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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