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Ferroquine
产品别名
185055-67-8
Ferroquine
1-[[(7-Chloro-4-quinolinyl)amino]methyl]-2-[(dimethylamino)methyl]-ferrocene
SSR 97193
7-Chloro-4-(((2-((dimethylamino)methyl)ferrocenyl)methyl)amino)quinoline
Ferrochloroquine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H24ClFeN3 |
| Molecular weight | 433.75 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Ferroquine (SSR 97193) is an antimalarial chloroquine analog effective against chloroquine-resistant Plasmodium falciparum. Ferroquine is thought to act by producing oxidative stress and by inhibiting the formation of hemozoin, produced by Malaria parasites as a disposal product of heme, which would otherwise be toxic to the Plasmodium cells. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | yellow to brown |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN(C)C[C]1[C]C[C][C]1CNC2=C(C=CC(Cl)=C3)C3=NC=C2.[C]4[C][C][C]C4.[Fe] |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P280 - P304 + P340 + P312 - P337 + P313 - P403 + P233 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
