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FIT-039
产品别名
1113044-49-7
FIT-039
FIT 039
FIT039
N-(5-Fluoro-2-(piperidin-1-yl)phenyl)pyridine-4-carbothioamide
N-[5-Fluoro-2-(1-piperidinyl)phenyl]-4-pyridinecarbothioamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H18FN3S |
| Molecular weight | 315.41 |
| MDL number | MFCD29770796 |
| Biochem/physiol Actions【生化/生理作用】 | FIT-039 is a potent and selective cyclin-dependent kinase 9 (CDK9) inhibitor that binds to the ATP -binding pocket of CDK9 and inhibits the kinase activity of P-TEFb complex. FIT-039 inhibits replication of herpes simplex virus 1 (HSV-1), HSV-2, human adenovirus, and human cytomegalovirus in cultured cells. FIT-039 ointment inhibits formation of skin legion in a mice HSV-1 infection model. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
