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Kevetrin hydrochloride
产品别名
66592-89-0
Kevetrin hydrochloride
4-Isothioureidobutyronitrile hydrochloride
Carbamimidothioic acid 3-cyanopropyl ester hydrochloride
NSC 525990 HCl
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C5H9N3S · HCl |
| Molecular weight | 179.67 |
| MDL number | MFCD22572767 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Kevetrin is an activator/stabilizer of wild type p53 tumor suppressor protein in human lung carcinoma and ovarian cancer cells that induces cell cycle arrest and apoptosis. Additionally Kevetrin down-regulates oncogenic mutant p53 in OVCAR-3 ovarian cancer cells. Kevetrin inhibits tumor growth in xenograft model of ovarian cancer. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 2 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | NC(SCCCC#N)=N.Cl |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
