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NITD008
产品别名
1044589-82-3
NITD008
7-(2-C-Ethynyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
7-Deaza-2′-C-acetylene-adenosine
NITD 008
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H14N4O4 |
| Molecular weight | 290.27 |
| MDL number | MFCD27952796 |
| Biochem/physiol Actions【生化/生理作用】 | NITD008 is a selective inhibitor of flaviviruses including dengue virus (EC50 = 0.64 μM), hepatitis C virus and Zika virus, and has also been shown to inhibit tick-borne flaviviruses in vitro. NITD008 has been reported to inhibit RNA-dependent RNA polymerase (RdRp), an essential protein of RNA viruses. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | NC1=C2C=CN(C2=NC=N1)[C@@H]3O[C@@H]([C@H]([C@](C#C)3O)O)CO |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
