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ONO-2506
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4086914 | 5 MG | 958 | |||
| 4086914 | 25 MG | 3360 |
产品别名
185517-21-9
ONO-2506
(R)-(-)-2-Propyloctanoic acid
ONO2506
ONO 2506
(2R)-2-Propyloctanoic acid
(-)-(2R)-2-Propyloctanoic acid
(R)-2-Propyloctanoic acid
Arundic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H22O2 |
| Molecular weight | 186.29 |
| MDL number | MFCD08458423 |
| Biochem/physiol Actions【生化/生理作用】 | ONO-2506 (arundic acid; (R)-2-propyloctanoic acid) is an inhibitory astrocytes-modulating agent that exerts glioprotective effects against amyloid-β-peptide (Aβ)-induced glial death in astrocyte cultures (50 μM ONO-2506 against 200 μM Aβ25-35, 24 hr; 1321N1 astrocytes) by decreasing both the intracellular and extracellular S100B levels. Blockade of astrocytic activation by ONO-2506 in vivo is shown to offer therapeutic efficacy in animal models of normal tension glaucoma (10 mg/kg po. mice), spinal cord injury (20 mg/kg/d ip or iv rats), brain seizure, ischemic stroke (10 mg/kg/d ip or iv rats), and Parkinson′s disease (30 mg/kg ip mice). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | oil |
| color【颜色】 | colorless to yellow |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
