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PA-6
产品别名
500715-03-7
PA-6
1,5-Bis[4-[[imino(phenyl)methyl]amino]phenoxy]pentane
Pentamidine-Analogue 6
N,N′-[1,5-Pentanediylbis(oxy-4,1-phenylene)]bis-benzenecarboximidamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C31H32N4O2 |
| Molecular weight | 492.61 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | PA-6 (Pentamidine-Analogue 6) is a selective and potent IK1 (inward rectifier potassium current) inhibitor that terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models. PA-6 interacts with the cytoplasmic pore region of the KIR2.1 (KCNJ2) ion channel. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | N=C(C1=CC=CC=C1)NC(C=C2)=CC=C2OCCCCCOC3=CC=C(NC(C4=CC=CC=C4)=N)C=C3 |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
