您的位置：首页 > 产品中心 > 457643-60-6， Rinvanil
Rinvanil
产品别名
457643-60-6
Rinvanil
(9Z,12R)-12-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-9-octadecenamide
N-Vanillylricinoleamide
基本信息
| Empirical Formula【经验(实验)分子式】 | C26H43NO4 |
| Molecular weight | 433.62 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Rinvanil is a Capsaicin analogue that potently activates transient receptor potential vanilloid 1 (TRPV1) channels. Rinvanil induces neuroprotective mild hypothermia in ischemic brain injured mice through TRPV1 activation. Rinvanil exhibits potent anticancer activity in cancer cell lines including cervical (HeLa, CaSKi, ViBo) and leukemia (P388, J774, WEHI-3) cell lines. Rinvanil is not cytotoxic to normal lymphocytes. TRPV1 (transient receptor potential vanilloid 1) is a capsaicin receptor. It is strongly expressed in sensory neurons and participates in pain perception. In brain, it regulates neuronal function, motor behaviour and neuroinflammation. Capsaicin plays an important role in the activation of TRPV1. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | oil |
| color【颜色】 | colorless to yellow |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
