您的位置：首页 > 产品中心 > 2055397-28-7， WM-1119
WM-1119
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4087123 | 5 MG | 1150 | |||
| 4087123 | 25 MG | 3400 |
产品别名
2055397-28-7
WM-1119
3-Fluoro-N′-(2-fluorophenyl)sulfonyl-5-(2-pyridyl)benzohydrazide
2-Fluoro-N′-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide
WM 1119
WM1119
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H13F2N3O3S |
| Molecular weight | 389.38 |
| MDL number | MFCD31690337 |
| Biochem/physiol Actions【生化/生理作用】 | WM-1119 is a potent and selective, acetyl coenzyme A (Acetyl-CoA)-competitive inhibitor against MYST family histone acetyltransferases KAT6A and KAT6B (KAT6B Kd = 2.1 nM by SPR, IC50 = 37 nM by activity assay; KAT7/5 Kd = 0.53/2.2 μM; no affinity toward 159 diverse biological targets). WM-1119 induces MEF G1 cell cycle arrest (1-10 μM), inhibits EMRK1184 lymphoma growth in cultures (IC50 = 250 nM) and in mice in vivo (50 mg/kg 3x or 4x i.p. per day). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | FC1=CC(C2=NC=CC=C2)=CC(C(NNS(C3=CC=CC=C3F)(=O)=O)=O)=C1 |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
