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依托哌嗪(Eltoprazine) 盐酸盐
Eltoprazine hydrochloride
产品别名
98206-09-8
依托哌嗪(Eltoprazine) 盐酸盐
Eltoprazine hydrochloride
1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H16N2O2 · HCl |
| Molecular weight | 256.73 |
| MDL number | MFCD06245586 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825943 |
| Biochem/physiol Actions【生化/生理作用】 | Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. It has Ki values for 5-HT1A, 5-HT1B and 5-HT1C receptors of 40 nM and 52 nM, respectively. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 10 mg/mL, clear |
| storage temp.【储存温度】 | room temp |
| SMILES string | [H]Cl.C1(OCCO2)=C2C(N3CCNCC3)=CC=C1 |
| InChI | 1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H |
| InChI key | JFSOSUNPIXJCIX-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 - H315 - H319 - H335 |
| Precautionary Statements | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
