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Anti-FGF-20 Antibody
| 产品编号： | 4087441 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-FGF-20 Antibody
Fibroblast growth factor 20, FGF-20
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | FGF-20 is a recent but important neurotrophic factor that regulates multiple central nervous system developmental systems and cell functions. It is a secreted protein expressed most highly in the cerebellum but also found in other regions. FGF-20 is a pro-survival factor on neurons and specifically has been shown to protect dopaminergic neurons against a range of toxic insults in vitro, through activation of fibroblast growth factor receptor 1 (FGFR1). FGF-20 treatments also appear to protect neurons in various disease models so it is being studied as a possible therapy. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human FGF-20 near theC-terminal. |
| Application【应用】 | This Anti-FGF-20 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of FGF-20. Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FGF-20 in human cerebral cortex, human cerebellum, and human thalamus tissue. |
| Quality【质量】 | Evaluated by Western Blotting in transfected HEK293 cell lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected FGF-20 in 10 µg of transfected HEK293 cell lysate. |
| Other Notes【其他说明】 | Affinity purified |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| species reactivity (predicted by homology) | guinea pig (based on 100% sequence homology), ferret (based on 100% sequence homology), rat (based on 100% sequence homology), mouse (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_062825 |
| UniProt accession no.【UniProt登记号】 | Q9NP95 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~30 kDa observed. Uncharacterized band(s) may appear in some lysates. |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
