您的位置：首页 > 产品中心 > Anti-Nogo Receptor Antibody
Anti-Nogo Receptor Antibody
产品别名
Anti-Nogo Receptor Antibody
Reticulon-4 receptor, Nogo receptor, NgR, Nogo-66 receptor, Nogor, Rtn4r
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Axons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord. |
| Specificity【特异性】 | Cat. # AB15138 recognizes the mature form of Nogo Receptor. May react with human and primate based on sequence homology. Reactivity with other species has not been determined. |
| Immunogen【免疫原】 | Recombinant protein. Epitope: Mature Form |
| Application【应用】 | Anti-Nogo Receptor Antibody detects level of Nogo Receptor & has been published & validated for use in WB, IH. Non-Lot Specific Tested Application 1: Immunohistochemistry: Working dilutions of 1:50-1:500 in rat brain and spinal cord (paraffin embedded) Research Category Neuroscience Research Sub Category Growth Cones & Axon Guidance |
| Quality【质量】 | Routinely tested on mouse cerebellum lysate. Lot Specific Tested Application 1: Western Blot |
| Physical form【外形】 | Format: Purified Protein A purified Purified in PBS with 0.1% NaN3 |
| Analysis Note【分析说明】 | Control Mouse cerebellum lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, rat, human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NM_022982 |
| UniProt accession no.【UniProt登记号】 | Q99PI8 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~50.9 kDa |
| Storage and Stability【储存及稳定性】 | Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
