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Anti-SARM Antibody
| 产品编号： | 4087498 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-SARM Antibody
Sterile alpha and TIR motif-containing protein 1, Sterile alpha and Armadillo repeat protein, Sterile alpha motif domain-containing protein 2, SAM domain-containing protein 2, Tir-1 homolog
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Sterile alpha and Armadillo repeat protein (SARM), also known as Sterile alpha and TIR motif-containing protein 1 (SARM1) and Sterile alpha motif domain-containing protein 2 (SAMD2), is involved in the innate immnune response. SARM blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. SARM is expressed kidney and liver with lower levels found in placenta. |
| Specificity【特异性】 | This antibody recognizes the C-terminus of SARM. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the C-terminus of human SARM. Epitope: C-terminus |
| Application【应用】 | Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected SARM in Daudi cells. Immunofluorescence Analysis: 2 µg/mL from a representative lot detected SARM in Daudi cells. Detect Sterile alpha & Armadillo repeat protein using this rabbit polyclonal antibody, Anti-SARM Antibody validated for use in western blotting, ICC & Immunofluorescence. Research Sub Category Immunoglobulins & Immunology Research Category Inflammation & Immunology |
| Quality【质量】 | Evaluated by Western Blotting in Daudi cell lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected SARM in 15 µg of Daudi cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Daudi cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable immunofluorescence: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q6SZW1 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... SARM1(23098) |
产品说明
| Target description【目标描述】 | ~89 kDa observed. Uncharacterized bands may appear in some lysates. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
