Anti-Neurotrypsin Antibody

32160702

NA.41

Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions. These functions include axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.

KLH-conjugated linear peptide corresponding to human Neurotrypsin.

Detect the Neurotrypsin protein using this Anti-Neurotrypsin validated for use in WB & IHC.
Western Blot Analysis: 1 µg/mL from a representative lot detected Neurotrypsin in 10 µg/mL of rat testis tissue lysate.

Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Neurotrypsin in human midbrain and rat cerebellum tissues.

Evaluated by Western Blot in mouse testis tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Neurotrypsin in 10 µg/mL of mouse testis tissue lysate.

Antigen Affinity Purified

300

rabbit

affinity isolated antibody

primary antibodies

polyclonal

affinity chromatography

rat, mouse, human

immunohistochemistry: suitable
western blot: suitable

P56730

wet ice

~97 kDa observed. Uncharacterized bands may appear at ~13 kDa, ~38 kDa, and ~43 kDa in some lysates.

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10 - Combustible liquids