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Anti-Sodium Channel NaV1.5 antibody produced in rabbit
| 产品编号： | 4087662 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 50 μL，200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Sodium Channel NaV1.5 antibody produced in rabbit
Anti-SCN5A
Anti-SKM2
基本信息
| MDL number | MFCD04975341 |
| NACRES | NA.41 |
| General description【一般描述】 | SCN5A (sodium voltage-gated channel α subunit 5) codes for an α subunit of the cardiac sodium channel (NaV1.5). It is located on human chromosome 3p22.2. |
| Immunogen【免疫原】 | peptide corresponding to amino acid residues 493-511 of rH1 (Accession P15389). This epitope is identical in mouse and highly homologous in human (17/19 residues identical). |
| Application【应用】 | Anti-Sodium Channel NaV1.5 antibody produced in rabbit has been in immunoblotting and immunofluorescence. |
| Biochem/physiol Actions【生化/生理作用】 | SCN5A (sodium voltage-gated channel α subunit 5) regulates the movement of sodium ions into cells, which helps in the production and diffusion of electrical impulses. SCN5A mutations results in the loss or gain of sodium channel activity and cause several cardiac diseases like Brugada syndrome, Long QT syndrome type 3, Sick sinus syndrome and progressive familial heart block. |
| Physical form【外形】 | Lyophilized at ~0.8 mg/mL in phosphate buffered, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | rat |
| technique(s) | western blot: 1:200 using rat heart membranes |
| UniProt accession no.【UniProt登记号】 | P15389 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SCN5A(6331) mouse ... Scn5a(20271) rat ... Scn5a(25665) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
