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Anti-BATF3 Antibody
| 产品编号： | 4087688 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-BATF3 Antibody
Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, Jun dimerization protein p21SNFT
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | BATF3, also known as Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, or Jun dimerization protein p21SNFT, and encoded by the gene BATF3/SNFT, is an AP-1 family transcription factor that controls the differentiation of CD8+ thymic conventional dendritic cells in the immune system. BATF3 is required for the development of CD8-alpha+ classical dendritic cells (cDCs) and related CD103+ dendritic cells that cross-present antigens to CD8. BATF3 acts via the formation of a heterodimer with JUN family proteins that recognizes and bind the DNA sequence 5′-TGA[CG]TCA-3′ and thus regulates the expression of the target genes. BATF3 is localized to the nucleus. BATF3 is expressed in myeloid dendritic cells and T cell precursor immune cells primarily. |
| Immunogen【免疫原】 | Epitope: Leucine-zipper KLH-conjugated linear peptide corresponding to the Leucine-zipper of human BATF3. |
| Application【应用】 | Research Sub Category Nuclear Receptors Flow Cytometry Analysis: 1 µg of this antibody detected BATF3 in human PBMC cells. Research Category Epigenetics & Nuclear Function Detect BATF3 using this Anti-BATF3 antibody validated for use in western blotting & flow cytometry. |
| Quality【质量】 | Evaluated by Western Blotting in human spleen tissue lysate. Western Blotting Analysis: 0.25 µg/mL of this antibody detected BATF3 in 10 µg of human spleen tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | flow cytometry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_061134 |
| UniProt accession no.【UniProt登记号】 | Q9NR55 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~17 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
