Anti-Bmf Antibody

32160702

NA.41

Bcl-2-modifying factor (Bmf) is a member of the Bcl-2 family containing one BCL2 homology domain 3. Members of this family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell′s actin cytoskeleton. Bmf is constitutively expressed in many tissues. There are 3 isoforms of Bmf. Isoform 1 is mainly expressed in B-lymphoid cells while isoform 2 and 3 are mainly expressed in B-CLL and normal B-cells.

This antibody recognizes the N-terminus of Bmf.

KLH-conjugated linear peptide corresponding to the N-terminus of human Bmf.

Immunocytochemistry Analysis: 10 µg/mL from a representative lot detected Bmf in HeLa cells.
Detect Bcl-2-modifying factor using this rabbit polyclonal antibody, Anti-Bmf Antibody validated for use in western blotting & IHC.

Evaluated by Western Blotting in HepG2 and HEK293 cell lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected Bmf in 15 µg of HepG2 and HEK293 cell lysates.

Antigen Affinity Purified

Control
HepG2 and HEK293 cell lysates

rabbit

100

affinity isolated antibody

primary antibodies

polyclonal

affinity chromatography

human

immunohistochemistry: suitable
western blot: suitable

Q96LC9

wet ice

human ... BMF(90427)

~25 kDa observed

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10 - Combustible liquids

WGK 2