Anti-LMX-1 Antibody

32160702

NA.41

LMX-1 is a transcription factor that belongs to the LIM-homeodomain (LIM-HD) transcription factor family. It is induced within the ventral midbrain as a response to early signaling. LMX-1 is a necessary component for the development of the roof plate and for CNS dorsal cell date specification and the development of vertebrae. It is Expressed in roof plate, an organizational locus found in the dorsal CNS that functions to moderate the differentiation and specification of adjacent neurons through the secretion of signaling molecules such as WNT and BMP. Recent studies have indicated that LMX-1 has high potential for stimulating the production of mesencephalic dopamine neurons(mesDA) for the therapeutic treatment Parkinson disease, a condition characterized by dopaminergic neurotransmission decline resulting from the progression of mesDA neuronal degeneration within the substantia nigra pars compacta (SN).

This antibody recognizes LMX-1.

Epitope: C-terminus
GST-tagged recombinant protein corresponding to the C-terminus of hamster LMX-1.

Research Sub Category
Neuronal & Glial Markers
Anti-LMX-1 Antibody is an antibody against LMX-1 for use in WB.
Research Category
Epigenetics & Nuclear Function

Evaluated by Western Blot in mouse testis tissue lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected LMX-1 on 10 µg of mouse testis tissue lysate.

Unpurified rabbit polyclonal serum containing 0.05% sodium azide.
Unpurified

Control
Mouse testis tissue lysate

GenBank is a registered trademark of United States Department of Health and Human Services

rabbit

100

serum

primary antibodies

polyclonal

mouse, rat

hamster (based on 100% sequence homology)

western blot: suitable

IgG

AAB62320

Q04650

wet ice

~50 kDa observed.

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

10 - Combustible liquids

WGK 1