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Anti-ARL13B Antibody
| 产品编号： | 4087803 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-ARL13B Antibody
ARL13B, ARL2-like protein 1, ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | ARL13B/ARL2L1 is an important neuronal developmental protein, as well as, a cilium-specific protein required for the control of the microtubule-based ciliary axoneme structure. ARL13B/ARL2L1 is required for proper patterning in neural development during neural tube formation, and ARL13B/ARL2L1 is critical for cerebral cortex development and the initial polarization of radial glia scaffold, the first step in cortex development. ARL13B/ARL2L1 also controls the migration and placement of post mitotic interneurons. ARL13B/ARL2L1 is found in cellular projections and cilium and is widely expressed in the developing system as well in the gut. ARL13B/ARL2L1 also is a member of the small GTPase superfamily as it binds GTP but does not cleave it. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human ARL13B. |
| Application【应用】 | Anti-ARL13B Antibody is an antibody against ARL13B for use in Immunohistochemistry and Immunocytochemistry. Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ARL13B in human cerebellum, embryonic mouse liver, and human cerebral cortex tissue. Research Category Neuroscience Research Sub Category Developmental Signaling |
| Quality【质量】 | Evaluated by Western Blotting in mouse E13-14 brain tissue lysate. Western Blotting Analysis: 2.0 µg/mL of this antibody detected ARL13B in 10 µg of mouse E13-14 brain tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_878899 |
| UniProt accession no.【UniProt登记号】 | Q3SXY8 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... ARL13B(200894) |
产品说明
| Target description【目标描述】 | ~60 kDa observed. Western blot shows the absence of a 60 kDa Arl13b band in Arl13bE9.5 (Humbert, M.C., et al. (2012). PNAS. 109(48):19691-19696). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
