您的位置：首页 > 产品中心 > Anti-BTG3 Antibody
Anti-BTG3 Antibody
| 产品编号： | 4087805 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-BTG3 Antibody
Protein BTG3, Abundant in neuroepithelium area protein, BTG family member 3, Protein Tob5
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | BTG3 is a tumor suppression protein because overexpression impairs serum-induced cell cycle progression from G0/G1 to the S phase in vitro. BTG3 is often down regulated in cancer cell lines, and thus BTG3 is a target for enhanced cancer therapy. In normal cells BTG3 inhibits cell proliferation, cell invasion, and angiogenesis, and also regulates cell-cycle progression and differentiation in a variety of cell types. Developmentally BTG3 is normally expressed primarily in the brain and CNS during development where is modulates cell proliferation. In the adult expression is high in ovary, testis, prostate, thymus and lung. It is not expressed strongly in many cancers. |
| Specificity【特异性】 | This antibodies immunogen is 94% identical in mouse and 92% identical in rat. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human BTG3. |
| Application【应用】 | Research Sub Category Apoptosis - Additional This Anti-BTG3 Antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of BTG3. Research Category Apoptosis & Cancer Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected BTG3 in human testis and human prostate tissue. |
| Quality【质量】 | Evaluated by Western Blotting in IMR-90 cell lysate. Western Blotting Analysis: A 1:500 dilution of this antibody detected BTG3 in 10 µg of IMR-90 cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_006797 |
| UniProt accession no.【UniProt登记号】 | Q14201 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... BTG3(10950) |
产品说明
| Target description【目标描述】 | ~37 kDa observed. Uncharacterized bands may be observed in some lysates. The calculated molecular weight of this protein is 29 kDa, but can be observed at ~37 kDa due to alternate splice variants. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
