您的位置：首页 > 产品中心 > Anti-FOXM1 Antibody
Anti-FOXM1 Antibody
| 产品编号： | 4087819 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-FOXM1 Antibody
Forkhead box protein M1, Forkhead-related protein FKHL16, Hepatocyte nuclear factor 3 forkhead homolog 11, HFH-11, HNF-3/fork-head homolog 11, M-phase phosphoprotein 2, MPM-2 reactive phosphoprotein 2, Transcription factor Trident, Winged-helix factor fr
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Forkhead box M1 (FOXM1), also named HNF-3, HFH-11 or Trident, belongs to a superfamily of Fox transcription factors. FOXM1 is strongly associated with cell proliferation and plays an important role in cell cycle progression by regulating both G1/S and G2/M phases. FOXM1 is also involved in DNA damage repair, angiogenesis, apoptosis, and tissue regeneration. Recently, crucial roles of this transcription factor were found in the development and progression of many cancers including colorectal, lung, prostate, liver and breast cancer. FOXM1 levels are significantly higher and associated with tumor grade in most human tumors, rendering it a potential target of cancer diagnosis and therapies. |
| Specificity【特异性】 | This antibody is expected to detect three known isoforms of FOXM1 based upon immunogen design. |
| Immunogen【免疫原】 | Epitope: Near C-terminus KLH-conjugated linear peptide corresponding to a region near the C-terminus of human FOXM1. |
| Application【应用】 | Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FOXM1 in human testis tissue. Research Sub Category Transcription Factors Anti-FOXM1 Antibody is an antibody against FOXM1 for use in western blotting, IHC & IP. Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Evaluated by Western Blotting in human thymus tissue lysate. Western Blotting Analysis: 0.25 µg/mL of this antibody detected FOXM1 in 10 µg of human thymus tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, mouse |
| species reactivity (predicted by homology) | monkey (based on 100% sequence homology), canine (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_973732 |
| UniProt accession no.【UniProt登记号】 | Q08050 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... FOXM1(2305), MPP2(4355) |
产品说明
| Target description【目标描述】 | ~88 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
