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Anti-Neuropilin-1 Antibody
产品别名
Anti-Neuropilin-1 Antibody
CD304 antigen, Vascular endothelial cell growth factor 165 receptor, neuropilin 1, transmembrane receptor, Npn 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Neuropilin-1 is a type 1 membrane protein with three distinct functions. First, it can mediate cell adhesion via a heterophilic molecular interaction. Second, in neuronal cells, neuropilin-1 binds the class 3 semaphorins, which are neuronal chemorepellents, and plays a role in the directional guidance of axons. It is expected to form complexes with the plexinA subfamily members and mediate the semaphorin-elicited inhibitory signals into neurons. Third, in endothelial cells, neuropilin-1 binds a potent endothelial cell mitogen, vascular endothelial growth factor (VEGF)165, and regulates vessel formation. |
| Specificity【特异性】 | This antibody recognizes Neuropilin-1. |
| Immunogen【免疫原】 | This antibody is generated from rabbits immunized with a His-tagged partial recombinant rat Neuropilin-1. Epitope: Unknown |
| Application【应用】 | Research Category Neuroscience Research Sub Category Growth Cones & Axon Guidance This Anti-Neuropilin-1 Antibody is validated for use in WB, IH, IP, IF for the detection of Neuropilin-1. |
| Quality【质量】 | Evaluated by Western Blot in PC12 cell lysate. Western Blot Analysis: : 1:1,000 dilution of this antibody detected Neuropilin 1 on 10 µg of PC12 cell lysate. |
| Physical form【外形】 | Unpurified Rabbit serum in buffer containing 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control PC12 cell lysate |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | serum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | rat, mouse |
| species reactivity (predicted by homology) | human (94%) |
| technique(s) | immunofluorescence: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NP_659566.1 |
| UniProt accession no.【UniProt登记号】 | Q9QWJ9 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... NRP1(8829) |
产品说明
| Target description【目标描述】 | 130 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
