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Anti-PRUNE Antibody
| 产品编号： | 4087863 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PRUNE Antibody
Protein prune homolog, hPrune, Drosophila-related expressed sequence 17, DRES-17, DRES17, HTcD37
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Protein prune homolog, otherwise known as PRUNE or Drosophila-related expressed sequence 17, is a phosphodiesterase enzyme belonging to the PPase class C family. PRUNE targets cAMP and cGMP second messengers and plays a role in cell proliferation and motility. It is overexpressed in various sarcomas, including leiomyosarcomas, malignant fibrous histiocytomas, and malignant liposarcomas. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human PRUNE. |
| Application【应用】 | Detect PRUNE using this Anti-PRUNE Antibody validated for use in Western Blotting. Research Sub Category Apoptosis - Additional Research Category Apoptosis & Cancer |
| Quality【质量】 | Evaluated by Western Blot in HeLa S3 cell lysate. Western Blot Analysis: A 1:5,000 dilution of this antibody detected PRUNE in 10 µg of HeLa S3 cell lysate. |
| Physical form【外形】 | Affinity purified Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control HeLa S3 cell lysate |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_067045 |
| UniProt accession no.【UniProt登记号】 | Q86TP1 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... PRUNE(58497) |
产品说明
| Target description【目标描述】 | ~57 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
