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Anti-PTBP2 Antibody
| 产品编号： | 4087864 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-PTBP2 Antibody
Polypyrimidine tract-binding protein 2, Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB, PTB-like protein
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Polypyrimidine tract-binding protein 2 (PTBP2) is also known as Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB and PTB-like protein. PTBP2 is a RNA-binding protein which targets intronic polypyrimidines and negatively regulates pre-mRNA, exonic splicing. PTBP2 also has a role in translational regulation. PTBP2 is mainly expressed in brain, but is also found in heart and skeletal muscle. Isoforms 1 and 2 are specifically expressed in neuronal tissues. |
| Specificity【特异性】 | This antibody recognizes the N-terminus of PTBP2. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the N-terminus of human PTBP2. Epitope: N-terminus |
| Application【应用】 | Research Sub Category Transcription Factors Anti-PTBP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Polypyrimidine tract-binding protein 2 & has been tested in western blotting & IP. Western Blotting Analysis: 0.5 µg/mL from a representative lot detected PTBP2 in 10 µg of rat brain cortex tissue lysate. Immunoprecipitation Analysis: 10ug from a representative lot immunoprecipitated PTBP2 in 500 µg of P19 cell lysate. Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Evaluated by Western Blotting in human cortex tissue lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected PTBP2 in 10 µg of human cortex tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Human cortex tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, rat, mouse |
| species reactivity (predicted by homology) | gorilla (based on 100% sequence homology), bovine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), canine (based on 100% sequence homology) |
| technique(s) | immunoprecipitation (IP): suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_067013 |
| UniProt accession no.【UniProt登记号】 | Q9UKA9 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... PTBP2(58155) |
产品说明
| Target description【目标描述】 | ~57 kDa observed. Uncharacterized band(s) may appear in some lysates. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
