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Anti-Frizzled 5 Antibody
产品别名
Anti-Frizzled 5 Antibody
Fz5, Fzd5
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | The Wnt family consists of ligands involved in cell fate determination, organogenesis, and oncogenesis. The Wnt signal is thought to be transduced sequentially via a homolog of the frizzled family of receptors to GSK-3 (disheveled), β- and γ- catenin and finally to members of the Tcf/Lef-1 family of HMG box transcription factors. Frizzled 5 is believed to function as the receptor for the Wnt5a ligand. |
| Specificity【特异性】 | Frizzled 5 (aka Fz5 or Fzd5) |
| Immunogen【免疫原】 | Epitope: C-Terminus KLH-conjugated, synthetic peptide derived from amino acids 564-585 of human Frizzled 5 (CTGRTPPGPAATYHKQVSLSHV). |
| Application【应用】 | Research Sub Category Developmental Signaling GPCR, cAMP/cGMP & Calcium Signaling Research Category Signaling Anti-Frizzled 5 Antibody is an antibody against Frizzled 5 for use in WB. |
| Quality【质量】 | Routinely evaluated by immunoblot on lysates from mouse liver, C2C12, Jurkat or HUVEC cells |
| Physical form【外形】 | Protein A chromatography Format: Purified Purified antibody in PBS with 0.05% sodium azide and 30% Glycerol |
| Analysis Note【分析说明】 | Control Lysates from mouse liver, C2C12, Jurkat, and HUVEC |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, rat, human |
| manufacturer/tradename | Upstate® |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NP_003459 |
| UniProt accession no.【UniProt登记号】 | Q13467 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... FZD5(7855) |
产品说明
| Target description【目标描述】 | Frizzled 5 (62kDa) |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
