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Anti-Ipaf (NLRC4) Antibody
| 产品编号： | 4088107 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μg |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Ipaf (NLRC4) Antibody
NLR family, CARD domain containing 4, NOD-like receptor C4, caspase recruitment domain family, member 12, ICE-protease activating factor, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4, NLR family CARD domain-
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Ipaf, also known as NLRC4, is a human CED-4 homologue and is thought to be an activator of pro-caspase-1 and might also be associated with the activation of caspase-1 as a response to pro-inflammatory and apoptotic stimulus. It has been shown to be induced by p53 and contributes to p53-dependent apoptosis. Ipaf is thought to play a role in the activation of the innate immune system. |
| Specificity【特异性】 | This antibody recognizes Ipaf at the LRR4 domain. |
| Immunogen【免疫原】 | Epitope: LRR4 domain KLH-conjugated linear peptide corresponding to human Ipaf (NLRC4) at the LRR4 domain. |
| Application【应用】 | Research Sub Category Apoptosis - Additional Western Blot Analysis: 1 ug/ml of this antibody detected Ipaf in 10 ug of human lung tissue lysate. Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected Ipaf in NIH/3T3 cells. Research Category Apoptosis & Cancer This Anti-Ipaf (NLRC4) Antibody is validated for use in IC, WB for the detection of Ipaf (NLRC4). |
| Quality【质量】 | Evaluated by Western Blot in human lung tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected Ipaf in 10 µg of human lung tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Human lung tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse, human |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_067032 |
| UniProt accession no.【UniProt登记号】 | Q9NPP4 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~112 kDa observed. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
