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产品别名
Anti-SRp40 Antibody
serine/arginine-rich splicing factor 5, Pre-mRNA-splicing factor SRP40, Delayed-early protein HRS, SR splicing factor 5, splicing factor, arginine/serine-rich 5
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | SRp40 is a nuclear phosphoprotein that is a member of the SR family of proteins. Essential for alternative splicing regulation this protein is also known as Serine/arginine-rich splicing factor 5, and Delayed-early protein HRS. The SRp40 protein is a component of the spliceosome complex and appears to play a role in splice site selection. Over-expression of SRp40 is thought to cause increased chondrogenic differentiation of mesenchymal cells. In addition, increased expression of SRp40 has been found in breast tumor tissues and is associated with alternative pre-mRNA splicing of CD44. |
| Immunogen【免疫原】 | Linear peptide corresponding to human SRp40. |
| Application【应用】 | Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in IP. (Jiang, K., et al. (2009). Endocrinology. 150(5):2087-2097.) Research Category Epigenetics & Nuclear Function Use Anti-SRp40 Antibody (Rabbit Polyclonal Antibody) validated in WB, IP to detect SRp40 also known as serine/arginine-rich splicing factor 5, Pre-mRNA-splicing factor SRP40. Research Sub Category RNA Metabolism & Binding Proteins |
| Quality【质量】 | Evaluated by Western Blot in HeLa cell lysate. Western Blot Analysis: 1:500 dilution of this antibody detected SRp40 on 10 µg of HeLa cell lysate. |
| Physical form【外形】 | Protein A Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified |
| Analysis Note【分析说明】 | Control HeLa cell lysate |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human, mouse |
| technique(s) | immunoprecipitation (IP): suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001034554 |
| UniProt accession no.【UniProt登记号】 | Q13243 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~38 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
