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Anti-TRIC-A Antibody
| 产品编号： | 4088246 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μg |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-TRIC-A Antibody
transmembrane protein 38A, trimeric intracellular cation channel type A, Tmem38a, NET1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | TRIC-A (trimeric intracellular cation channel type A), also known as Tmem38A, and sometimes NET1, is one of a number of TRIC channel subtypes that are believed to function as a Ca2+ counter-ion channel. TRIC-A is highly expressed in excitable cells and seems to work in coordination with Ca2+ release to balance transient negative potential. TRIC-A is located on the sarcoplasmic reticulum (SR) and is thought to be regulated by trans-membrane voltage. TRIC-A deficiency may lead to an abundance of Ca2+ and cause volatility in Ca2+ movement across the SR membrane. |
| Specificity【特异性】 | This antibody recognizes the cytoplasmic domain of TRIC-A. |
| Immunogen【免疫原】 | Epitope: Cytoplasmic domain KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human TRIC-A. |
| Application【应用】 | Research Sub Category GPCR, cAMP/cGMP & Calcium Signaling Anti-TRIC-A Antibody detects level of TRIC-A & has been published & validated for use in WB, IH & IC. Research Category Epigenetics & Nuclear Function Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in IH. (Wilkie, G.S., et al. (2011). Mol Cell Proteomics. 10(1):M110.003129-1). Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in IC. (Wilkie, G.S., et al. (2011). Mol Cell Proteomics. 10(1):M110.003129-1). |
| Quality【质量】 | Evaluated by Western Blot in human fetal skeletal muscle tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected TRIC-A on 10 µg of human fetal skeletal muscle tissue lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in PBS containing 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control Human fetal skeletal muscle tissue lysate. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | rat, human, mouse |
| species reactivity (predicted by homology) | chimpanzee (based on 100% sequence homology) |
| technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_076979.1 |
| UniProt accession no.【UniProt登记号】 | Q9H6F2 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~33 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
