Anti-Hox A9 Antibody

32160702

NA.41

HOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa-9 markedly expands hematopoietic stem cells. HOXA9 expression changes dramatically with age - a uniformly low level of expression during early adulthood is replaced by a frequently very high expression in adults over sixty.

Hox A9
Based on a BLAST search, the antibody will likely cross react with Newt, Coelacanth, Dog, Chicken, and Rat Hox A9; Antelope, Mouse and Guinea Pig Hox 1.7; Frog, human and Zebrafish Hox A-9B; and Kenyan Clawed Frog Hox B.1

GST fusion protein corresponding to residues 194-272 of mouse Hox A9

Research Sub Category
Transcription Factors
Detect Hox A9 with Anti-Hox A9 Antibody (Rabbit Polyclonal Antibody), that has been shown to work in EMSA, WB, ICC.
Research Category
Epigenetics & Nuclear Function

Routinely evaluated by immunoblot on whole cell lysates of Hoxa9 immortalized HF1 myeloid progenitor cells

Protein A purified immunoglobulin presented in 0.02M phosphate buffer, pH 7.6, 0.25M NaCl, and 0.1% Sodium Azide before the addition of glycerol to 30%.
Protein A chromatography
Format: Purified

Control
Hoxa9 immortalized HF1 cells

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

rabbit

100

purified immunoglobulin

primary antibodies

polyclonal

mouse, human

Upstate^®

electrophoretic mobility shift assay: suitable
immunocytochemistry: suitable
western blot: suitable

IgG

NM_152739

P31269

wet ice

human ... HOXA9(3205)

36kDa

2 years at -20°C

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10 - Combustible liquids

WGK 2