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Anti-Phosphothreonine-Proline Antibody
| 产品编号： | 4088528 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μg |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Phosphothreonine-Proline, along with similar motifs involving serine/threonine residues preceding proline undergoing phosphorylation, has critical roles in the moderation of various cellular processes, protein function, and kinases through proline-directed phosphorylation. The deregulation of proline-directed phosphorylation is known to be a factor in diseases such as cancer and Alzheimer’s neurodegeneration. |
| Specificity【特异性】 | Recognizes the phosphorylated phothreonine-proline motif, which is the site of phosphorylation of many proline-directed protein kinase such MAPK and cyclin-dependent protein kinases. Also recognizes the phosphoserine-proline motif to a similar degree. |
| Immunogen【免疫原】 | KLH-phosphothreonine-proline amide (pT-P-NH2) peptide conjugates |
| Application【应用】 | Detect Phosphothreonine-Proline using this Anti-Phosphothreonine-Proline Antibody validated for use in WB. |
| Quality【质量】 | Evaluated by Western Blot in Calyculin treated Jurkat cell lysate. Western Blot Analysis: 1:500 dilution of this lot detected phosphorylated proteins on 10 μg of calyculin treated Jurkat lysates. |
| Linkage【联系】 | Replaces: AB3192 |
| Physical form【外形】 | Liquid in TBS with 0.05% sodium azide and 50% glycerol. Affinity purified |
| Analysis Note【分析说明】 | Control Calyculin treated Jurkat cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | rat, human, mouse |
| technique(s) | western blot: suitable |
| shipped in【运输】 | wet ice |
产品说明
| Storage and Stability【储存及稳定性】 | Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage. |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
