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Fmoc-TOAC-OH
产品别名
93372-25-9
Fmoc-TOAC-OH
2,2,6,6-Tetramethylpiperidine-N-oxyl-4-(9-fluorenylmethyloxycarbonyl-amino)-4-carboxylic acid
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H29N2O5 |
| Molecular weight | 437.51 |
| General description【一般描述】 | Fmoc-TOAC-OH is a useful tool for the incorporation of the ESR spin-label TOAC into peptide sequences [1]. Incorporation of this derivative and the following residue is best achieved using HATU activation. TFA/water/TIS should be used for cleavage of TOAC-containing peptides. The use of EDT should be avoided as it can cause permanent reduction of the nitroxide radical [2]. Following cleavage, the TOAC peptide should be treated with aqueous ammonia in air to regenerate the nitroxide from the hydroxylamine that is generated by the TFA treatment. |
| Analysis Note【分析说明】 | Color (visual): white to yellow to beige Appearance of substance (visual): powder Identity (IR): passes test Assay (HPLC, area%): ≥ 98.0 % (a/a) |
| Legal Information【法律信息】 | Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 200 |
| product line【产品线】 | Novabiochem® |
| Assay【测定】 | ≥98.0% (HPLC) |
| form【形式】 | powder |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| manufacturer/tradename | Novabiochem® |
| functional group【官能团】 | Fmoc |
| storage temp.【储存温度】 | 2-8℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
