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Fmoc-Glu-ODmab

产品编号:4089639
规格:Novabiochem®
CAS NO:172611-75-5
包装规格:5 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40896395 G9150
产品别名

172611-75-5

Fmoc-Glu-ODmab

N-α-Fmoc-L-glutamic acid α-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester

基本信息
Empirical Formula【经验(实验)分子式】
C40H44N2O8
Molecular weight
680.79
General description【一般描述】
Quasi-orthogonally-protected Glu derivative.

The Dmab group can be removed selectively in the presence of tBu-based protecting groups by treatment with 2% hydrazine in DMF [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(ivDde) and Glu(ODmab) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.

The product number for this product was previously 04-12-1174.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Linkage【联系】
Replaces: 04-12-1174
Analysis Note【分析说明】
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 90 %
Purity (TLC(0811)): ≥ 90 %
Assay (HPLC, area%): ≥ 96.0 % (a/a)
For TLC-Systems see our General Catalog
Legal Information【法律信息】
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
Quality Level【质量水平】
200
product line【产品线】
Novabiochem®
Assay【测定】
≥90% (TLC)
≥96.0% (HPLC)
form【形式】
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group【官能团】
Fmoc
storage temp.【储存温度】
15-25℃
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 2
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