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Fmoc-Dpr(ivDde)-OH
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4089830 | 1 G | 2340 |
产品别名
607366-20-1
Fmoc-Dpr(ivDde)-OH
N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-diaminopropionic acid
基本信息
Empirical Formula【经验(实验)分子式】 | C31H36N2O6 |
Molecular weight | 532.63 |
General description【一般描述】 | This orthogonally-protected diaminopropionic acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains [1]. However, migration from side-chain to the unprotected α-amino group of Dpr is unavoidable [2]. This side-reaction can, however, be minimized by the appropriate choice of coupling method for the subsequent residue, see [3]. When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [4]. The product number for this product was previously 04-12-1195. To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. |
Linkage【联系】 | Replaces: 04-12-1195 |
Analysis Note【分析说明】 | Color (visual): white to slight yellow to beige Appearance of substance (visual): powder Identity (IR): passes test Enantiomeric purity: ≥ 99.5 % (a/a) Purity (TLC(157A)): ≥ 98 % Purity (TLC(CMA2)): ≥ 98 % Assay (HPLC, area%): ≥ 99.0 % (a/a) Solubility (1 mmole in 2 ml DMF): clearly soluble Assay (acidimetric): ≥ 95.0 % Water (K. F.): ≤ 1.00 % For TLC-Systems see our General Catalog |
Legal Information【法律信息】 | Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 200 |
product line【产品线】 | Novabiochem® |
Assay【测定】 | ≥95.0% (acidimetric) ≥98% (TLC) ≥99.0% (HPLC) |
form【形式】 | powder |
reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
manufacturer/tradename | Novabiochem® |
application(s) | peptide synthesis |
functional group【官能团】 | Fmoc |
storage temp.【储存温度】 | 15-25℃ |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 2 |