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Fmoc-Tyr(PO(NMe2)2)-OH
产品别名
172611-23-3
Fmoc-Tyr(PO(NMe2)2)-OH
N-α-Fmoc-O-(bis-dimethylamino-phosphono)-L-tyrosine
基本信息
| Empirical Formula【经验(实验)分子式】 | C28H32N3O6P |
| Molecular weight | 537.54 |
| General description【一般描述】 | Fmoc-Tyr(PO(NMe2)2)-OH is a useful derivative for the synthesis of phosphotyrosine-containing peptides by Fmoc SPPS [1]. As the side-chain phosphate group is fully protected, this derivative is compatible with all coupling methods. Regeneration of phosphotyrosine from the phosphodiamidate is effected by acid catalyzed hydrolysis using 90% aq. TFA. The product number for this product was previously 04-12-1205. To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. |
| Linkage【联系】 | Replaces: 04-12-1205 |
| Analysis Note【分析说明】 | Color (visual): white to slight yellow to beige Appearance of substance (visual): powder Identity (IR): passes test Enantiomeric purity: ≥ 99.5 % (a/a) Purity (TLC(0811)): ≥ 98 % Assay (HPLC, area%): ≥ 96.0 % (a/a) Solubility (1 mmole in 2 ml DMF): clearly soluble Assay (acidimetric): ≥ 93.0 % Water (K. F.): ≤ 4.5 % Ethyl acetate (HS-GC): ≤ 0.5 % Acetate (IC): ≤ 0.1 % For TLC-Systems see our General Catalog |
| Legal Information【法律信息】 | Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 200 |
| product line【产品线】 | Novabiochem® |
| Assay【测定】 | ≥93.0% (acidimetric) ≥96.0% (HPLC) ≥98% (TLC) |
| form【形式】 | powder |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| manufacturer/tradename | Novabiochem® |
| application(s) | peptide synthesis |
| functional group【官能团】 | Fmoc |
| storage temp.【储存温度】 | 15-25℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
