Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)

32160702

NA.41

Asymmetrical dimethlarginine (ADMA) is an endogenous, L-arginine metabolite arising from the proteolysis of methylated arginine containing proteins and is a known inhibitor of nitric oxide synthase (NOS). In various studies, ADMA has been observed as having a regulatory role in cell motility and the actin cytoskeleton. Elevated levels of ADMA are associated with sporadic FSGS, coronary artery disease, hypertension, peripheral arterial occlusive disease, obesity, stroke, preeclampsia, and cardiovascular mortality/morbidity in patients with diabetic nephropathy.

This antibody recognizes dimethylated arginines.

KLH-conjugated linear peptide containing asymmetric dimethyl-arginine-glycine repeats.

Detect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.

Evaluated by Western Blot in PRMT1 treated and untreated MEF cell lysates.

Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.

Unpurified

rabbit

100

serum

primary antibodies

polyclonal

mouse

rat (based on 100% sequence homology), human (based on 100% sequence homology)

western blot: suitable

wet ice

Multiple. This antibody detects proteins containing asymmetrical dimethylated arginines.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

10 - Combustible liquids

WGK 1