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产品别名
Anti-PADI4 Antibody, CT
HL-60 PAD, PADI-H protein, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, peptidyl arginine deiminase, type IV, peptidyl arginine deiminase, type V, protein-arginine deiminase, Protein-arginine deiminase type-4
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | PADI4 (Protein-arginine deiminase type-4) is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalysis of the deimination of the arginine residues. PADI4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response. |
| Specificity【特异性】 | The antibody recognizes PADI4 at and around the C-terminus. |
| Immunogen【免疫原】 | KLH-conjugated synthetic linear peptide corresponding to the C-terminal region of PADI4. Epitope: C-terminus |
| Application【应用】 | Anti-PADI4 Antibody, C-terminus is an antibody against PADI4 for use in WB, ELISA. ELISA: A 1:1000 dilution of a previous lot was used on ELISA. Research Sub Category Histones Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Evaluated by western blot on HEK293 cell lysate. Western Blotting Analysis: 1:25-1:500 dilution of this antibody detected PADI4 in HEK293 cell lysate. |
| Physical form【外形】 | Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Format: Purified Purified rabbit polyclonal in buffer containing PBS and 0.09% sodium azide. |
| Analysis Note【分析说明】 | Control HEK293 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human |
| technique(s) | ELISA: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_036519 |
| UniProt accession no.【UniProt登记号】 | Q9UM07 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~74 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 6 months at 2-8ºC from date of receipt. For long term storage, store at -20ºC |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
