Anti-SUMO-1 Antibody

32160702

The small ubiquitin-related modifier SUMO-1 belongs to the growing family of ubiquitin-related proteins involved in post translational protein modification1. It is present in all eukaryotic kingdoms and is highly conserved from yeast to humans. SUMO-1 does not appear to target proteins for degradation but seems to be involved in the modulation of protein-protein interactions. An increasing number of SUMO-1 substrates are being described but three major substrates for SUMO-1 modification are RanGAP1 and PML proteins.

Recognizes SUMO-1. This antibody shows no cross-reactivity with ubiquitin, multi-ubiquitin chains, SUMO2/3, UCRP, Nedd8, and FAT10.

Synthetic peptide corresponding to amino acid residues 11-101 of human SUMO-1.

Anti-SUMO-1 Antibody detects level of SUMO-1 & has been published & validated for use in WB.

Replaces: 04-453

Salt precipitation
100 µL of purified by salt precipitation in PBS containing 0.01% sodium azide. Dilute to working strength with 50mM Tris-HCl buffer (pH 7.6) containing 1.5% sodium chloride and 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used).
Format: Purified

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

rabbit

100

purified antibody

primary antibodies

polyclonal

all

Upstate^®

western blot: suitable

IgG

NM_001005781.1
NM_001005782.1
NM_003352.4

P63165

dry ice

human ... SENP2(59343), SUMO1(7341)

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10 - Combustible liquids

WGK 2