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Anti-TGIF2 Antibody
产品别名
Anti-TGIF2 Antibody
TGFB-induced factor homeobox 2, transcription growth factor-beta-induced factor 2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | TGIF2 (TGFbeta-induced transcription factor 2) is a homeobox protein that represses transcription by directly binding the DNA sequence 5′-CTGTCAA-3′ or by interacting with the transcriptional modulator SMAD3. TGIF2 also is thought to repress transcription via the recruitment of histone deacetylase proteins. TGIF2 is phosphorylated in response to EGF signaling by the Ras/MAPK pathway. TGIF2 is amplified and overexpressed in several ovarian cancer cell lines. |
| Specificity【特异性】 | Recognizes TGIF2 |
| Immunogen【免疫原】 | Epitope: a.a. 189-203 KLH conjugated synthetic peptide (C)-EQDKEDFSSFQLLVE corresponding to a.a. 189-203 of human TGIF. |
| Application【应用】 | Research Sub Category Transcription Factors Anti-TGIF2 Antibody is a Rabbit Polyclonal Antibody for detection of TGIF2 also known as transcription growth factor-beta-induced factor 2 & has been validated in WB. Research Category Epigenetics & Nuclear Function |
| Quality【质量】 | Routinely evaluated by immunoblot. |
| Physical form【外形】 | Immunoaffinity purified rabbit IgG in PBS, 0.1% sodium azide, 30% glycerol ImmunoAffinity Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse, rat, human |
| manufacturer/tradename | Upstate® |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9GZN2 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... TGIF2 (60436) mouse ... TGIF2(228839) rat ... TGIF2 (499929) |
产品说明
| Target description【目标描述】 | 28 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
