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AMPK (α1/β2/γ1), active, His tagged human
| 产品编号： | 4090320 |
| 规格： | PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
AMPK (α1/β2/γ1), active, His tagged human
MGC61468
MGC33776
AMPKg
PRKAA1
PRKAB2
MGC8666
MGC57364
PRKAG1
基本信息
| NACRES | NA.32 |
| Biochem/physiol Actions【生化/生理作用】 | AMPK (A1/B2/G1) is a member of the AMPK family which are heterotrimeric proteins consisting of an α catalytic subunit, and non-catalytic β and γ subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress. AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and 3-hydroxy-3-methylglutaryl-CoA reductase. The β subunit may be a positive regulator of AMPK activity and is highly expressed in skeletal muscle. |
| Physical form【外形】 | Supplied in 50 mM Sodium Phosphate, pH 7.0, with 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, and 25% glycerol. |
| Legal Information【法律信息】 | PRECISIO is a registered trademark of sigma-aldrich Co. LLC |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
| product line【产品线】 | PRECISIO® Kinase |
| Assay【测定】 | ≥70% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| Specific Activity | 297-401 nmol/min·mg |
| mol wt【分子量】 | A1 subunit ~68 kDa B2 subunit ~36 kDa G1 subunit ~40 kDa |
| UniProt accession no.【UniProt登记号】 | O43741 P54619 Q13131 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... PRKAA1(5562), PRKAB2(5565), PRKAG1(5571) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
