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Human Internal Thoracic Artery Endothelial Cells: HITAEC, adult
基本信息
| NACRES | NA.81 |
| General description【一般描述】 | HITAEC has been used to investigate oral pathogens travel through the body by infecting dendritic cells and inducing them to migrate through endothelial layers by causing upregulation of CXCR4 (Miles, 2014). To identify genes that make Human Internal Thoracic Arteries resistant to atherosclerosis, HITAEC and HCAEC (derived from the athero-prone human coronary arteries) were subjected to microarray analysis (Archaki, 2012). Twenty-nine genes were found to be expressed differently between HITAEC and HCAEC; one of them (TES) was shown to be downregulated in patients with coronary artery disease, resulting in increased monocyte adhesion, endothelial cell motility and transendothelial migration of monocytes. |
| Cell Line Origin【细胞系来源】 | Artery |
| Application【应用】 | coronary artery bypass grafting, myocardial revascularization, endothelial cell motility, transendothelial migration, gene expression, contractile responses, receptor stimulation, cell relaxation, supply of oxygenated blood to chest wall and breasts, |
| Components【组分】 | Basal Medium containing 10% FBS & 10% DMSO |
| Preparation Note【制备说明】 |
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| Subculture Routine【传代培养常规】 | Please refer to the HITAEC Culture Protocol. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | human intrathoratic artery (normal) |
| packaging【包装】 | pkg of 500,000 cells |
| growth mode【生长模式】 | Adherent |
| karyotype【核型】 | 2n = 46 |
| morphology【形态学】 | Endothelial |
| technique(s) | cell culture | mammalian: suitable |
| relevant disease(s)【相关疾病】 | diabetes; cardiovascular diseases |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −196℃ |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
