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Human Chondrocytes-Rheumatoid Arthritis: HC-RA, adult
基本信息
| NACRES | NA.81 |
| General description【一般描述】 | HC-RA Human Chondrocytes are derived from human articular cartilage of donors with rheumatoid arthritis (RA). Rheumatoid arthritis is an inflammatory disease that is characterized by overproliferation of synovial cells and their infiltration into adjacent joint tissues, accompanied by gradual destruction of cartilage and bone erosion. Normally, chondrocytes are responsible for producing and maintaining the extracellular matrix of cartilage, but in RA cartilage, the environment is changed significantly due to inflammation and the invasion of other cells. Therefore, HC-RA can be a useful model to study the effects of those changes on chondrocyte biology. In parallel with normal HC, HC-RA can be used to investigate the differences between normal and pathological joints and evaluate potential treatment strategies. Characterization: Positive for aggrecan after differentiation. |
| Cell Line Origin【细胞系来源】 | Cartilage |
| Application【应用】 | model to study effects of RA on chondrocytes, investigate differences between normal and pathological joints and evaluate potential treatment strategies |
| Components【组分】 | Basal Medium containing 10% FBS & 10% DMSO |
| Preparation Note【制备说明】 |
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| Subculture Routine【传代培养常规】 | Please refer to the HC-RA Culture Protocol. |
产品性质
| biological source【生物来源】 | human articular cartilage (rheumatoid arthritic) |
| Quality Level【质量水平】 | 100 |
| packaging【包装】 | pkg of 500,000 cells |
| growth mode【生长模式】 | Adherent |
| karyotype【核型】 | 2n = 46 |
| morphology【形态学】 | chondrocyte |
| technique(s) | cell culture | mammalian: suitable |
| relevant disease(s)【相关疾病】 | arthritis |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −196℃ |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
