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产品性质
| biological source【生物来源】 | rat lung |
| packaging【包装】 | pkg of 500,000 cells |
| growth mode【生长模式】 | Adherent |
| morphology【形态学】 | fibroblast |
| technique(s) | cell culture | mammalian: suitable |
| relevant disease(s)【相关疾病】 | asthma; tuberculosis; cancer; cardiovascular diseases |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −196℃ |
基本信息
| General description【一般描述】 | RLF from Cell Applications, Inc. have been used to demonstrate that exaggerated (compared to adults) NF-κB activation in neonates in response to hyperoxia is mediated by phosphorylation of IκBα on Tyr42 (Wright, 2009). They were also used to elucidate melatonin effects and signaling pathway (Ben Soussia, 2012) and served as a control in studies investigating epithelial-mesenchimal transition as the source of myofibroblasts responsible for idiopathic pulmonary fibrosis (Willis, 2005; Jain, 2007). |
| Cell Line Origin【细胞系来源】 | Lungs |
| Application【应用】 | Pulmonary function, gene expression, healing & repair process, differentiation, extracellular matrix production, growth factor and cytokine activation, actin reorganization, synthesis of type II collagen, elastin, and proteoglycans, airway remodeling, pharmaceutical development. |
| Components【组分】 | Rat Fibroblast Basal Medium that contains 10% FBS and 10% DMSO |
| Quality【质量】 | Each lot was tested for proper morphology, Population Doublings, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi. |
| Preparation Note【制备说明】 |
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| Subculture Routine【传代培养常规】 | Please refer to the RLF Culture Protocol. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
