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Insulin-Like Growth Factor Binding Protein-2 human
| 产品编号： | 4091266 |
| 规格： | recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, ≥95% (SDS-PAGE) |
| 包装规格： | 25 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Insulin-Like Growth Factor Binding Protein-2 human
IGFBP-2
基本信息
| MDL number | MFCD02099094 |
| NACRES | NA.32 |
| General description【一般描述】 | The gene IGFBP-2 (insulin-like growth factor binding protein-2) is mapped to human chromosome 2q35. |
| Biochem/physiol Actions【生化/生理作用】 | IGFBP-2 (insulin-like growth factor binding protein-2) regulates the function of IGF ligands. IGFBP2 is associated with skeletal muscle cell proliferation and differentiation. It also plays an important role in the differentiation of corneal fibroblast. During development, insulin-like growth factor binding protein-2 is expressed in a number of tissues with the highest expression level found in the central nervous system. IGFBP-2 exhibits a 2-10 fold higher affinity for IGF II than for IGF I. Mouse and human IGFBP-2 share approximately 82% homology. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution of 30% (v/v) acetonitrile with 0.1% (v/v) TFA |
| Analysis Note【分析说明】 | The biological activity is measured by its ability to inhibit recombinant human lGF-II on MCF-7 cells. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in NSO cells |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | lyophilized powder |
| potency【效能】 | 0.04 μg/mL |
| mol wt【分子量】 | ~36 kDa by SDS-PAGE calculated mol wt ~31 kDa |
| packaging【包装】 | pkg of 25 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| technique(s) | cell culture | mammalian: suitable |
| impurities【杂质】 | endotoxin, tested |
| UniProt accession no.【UniProt登记号】 | P18065 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IGFBP2(3485) |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H319 - H332 |
| Precautionary Statements | P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Inhalation - Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
